细胞因子重组蛋白

Recombinant Rat Resistin

Recombinant Rat Resistin

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Recombinant Rat Resistin

产品详情

产品编号:QC400-35
产品描述:

Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that resistin expression is severely suppressed in obesity, and that it may act as a feedback regulator of Adipogenesis. Recombinant Rat Resistin is a 20.0 kDa, disulfide-linked, homodimeric protein composed of two 94 identical amino acid chains linked by a single disulfide bond.

Source: E.coli

 

 

Synonyms: FIZZ3, Adipose tissue-specific secretory factor, ADSF 

 

 

AA Sequence (monomer): PSMSLCPMDE AISKKINQDF SSLLPAAMKN TVLHCWSVSS RGRLASCPEG TTVTSCSCGS GCGSWDVRED TMCHCQCGSI DWTAARCCTL RVGS 

 

 

Purity: ≥ 97% by SDS-PAGE gel and HPLC analyses. 

 

 

Biological Activity: Not available.